Sub-millimeter T2 weighted fMRI at 7 T: comparison of 3D-GRASE and 2D SE-EPI

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Sub-millimeter T2 weighted fMRI at 7 T: comparison of 3D-GRASE and 2D SE-EPI

Functional magnetic resonance imaging (fMRI) allows studying human brain function non-invasively up to the spatial resolution of cortical columns and layers. Most fMRI acquisitions rely on the blood oxygenation level dependent (BOLD) contrast employing T(*) 2 weighted 2D multi-slice echo-planar imaging (EPI). At ultra-high magnetic field (i.e., 7 T and above), it has been shown experimentally a...

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Anatomical imaging at 7 T using 2D GRASE – A Comparison with 2D TSE

Introduction: GRASE (Gradient-and Spin-Echo) [1] imaging has recently been used successfully for perfusion measurements [2] and functional MRI [3]. However, due to known blurring and ringing artifacts [4] GRASE still awaits a breakthrough in structural imaging [5-7]. At high field strengths such as 7 T, many imaging sequences are limited in their spatial coverage per unit time, due to their hig...

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Introduction: It has been hypothesized that T2-weighted BOLD fMRI at ultra-high field shows higher spatial specificity than T2*weighted BOLD, since the main signal contribution is expected to come from the extravascular spins of the microvasculature [1-3]. Unfortunately, the number of slices that can be acquired in multi-slice SE-EPI is often highly limited at ultra-high field due to SAR constr...

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Comparison of single-shot 2D EPI and segmented 3D EVI acquisition for fMRI at 7T

Introduction Echo volumar imaging (EVI) has been demonstrated to be an attractive tool for high spatiotemporal fMRI. Compared to 2D single shot acquisitions, EVI benefits from increased SNR due to the volume excitation. At the same time, however, increased signal fluctuations (physiological noise) have been observed in segmented 3D spiral fMRI investigations, which counteract the SNR gain of th...

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ژورنال

عنوان ژورنال: Frontiers in Neuroscience

سال: 2015

ISSN: 1662-453X

DOI: 10.3389/fnins.2015.00163